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Research Involving Human Embryos Regulations 2017
7DDefinition of pronuclear transfer
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7D Definition of pronuclear transfer
Pronuclear transfer is a technique that involves taking the following steps, without intentionally modifying any nuclear DNA or mitochondrial DNA: (a) fertilising, with a human sperm, a human egg of a woman to create a zygote (zygote A); (b) removing the pronuclei from zygote A; (c) fertilising, with a human sperm, a human egg of a different woman to create another zygote (zygote B); (d) removing the pronuclei from zygote B; (e) implanting the pronuclei from zygote A into zygote B, while seeking to minimise carryover of mitochondria from zygote A to zygote B.