phenyl-quinolin-carboxylic acid, has been found of service in the
elimination of uric acid and has been greatly employed in cases of gout
and sometimes for the relief of pain arising from other conditions.
Its use originated in Germany in 1908, and became general. But
in 1922 some doubts were started as to the safety of the drug because
it was suspected of having caused some cases of acute yellow jaundice.
These doubts were renewed in 1926, and, as a result of observation
and experience, a number of papers have been contributed to the
medical journals of Great Britain and America supporting the
conclusion that the administration of the drug is attended with some
tisk of the patient contracting that complaint, either because of a
pre-existing hepatic condition, or because of a too great or prolonged
use of the drug, or because of some natural idiosyncrasy. These
cautions from British and American medical authorities do not
appear to have been circulated in France until 1928; and it is not
at all clear when and to what extent they were communicated to
the profession in Germany, where the remedy seems to have been
touch used. The respondent was, probably, quite unaware that
any medical opinion existed that some risk was involved in using
the drug, which, in South Australia, was on sale in tablet form at
chemists and other shops. He prescribed the preparation very
freely among his patients, and he did not adopt some of the precau-
tions which are now recommended before doing so. But, notwith-
standing the appellants' efforts to find evidence to the contrary, his
administration of the drug appears to have proved injurious to no
one, although one patient who began to take it did immediately
show symptoms of constitutional intolerance for it. The numbers of
the Medical Journal of Australia for 27th April and Ist June 1929
contained a discussion of evil consequences ascribed to atophan
and cinchophen preparations, whereupon there appeared in a
Sydney daily paper some articles upon the risks to which the sale
of the drug exposed the public. These articles came into the hands
of a medical man who practised in the same town as the respondent,
and he at once visited the office of the appellants, who published
newspapers in Sydney, one of which, a weekly, circulated in South
Australia, The appellants, as the result of this visit, proceeded to